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目的了解新余市出生缺陷的可疑因素及产前诊断现状,提出干预措施和提高产前诊断率的对策。方法回顾性统计新余市2001～2011年出生缺陷情况,分析出生缺陷率、出生缺陷发生顺住与构成比及产前诊断情况。结果 72514例围产儿中,出生缺陷儿481例,出生缺陷发生率66.33/万;随孕母年龄增加,围产儿的出生缺陷发生率升高(χ2=45.63,P<0.05),35岁以上缺陷发生率明显增高(P<0.05);孕母文化程度越低,出生缺陷的发生机会越大(RR=4.59);出生缺陷围产儿死亡高于非出生缺陷围产儿(RR=16.21);产前诊断的出生缺陷儿有151例(31.39%)。结论新余市出生缺陷发生率偏高,产前诊断率偏低,提高产前诊断水平已是势在必行。
Objective To understand the suspicious factors of birth defects and the status of prenatal diagnosis in Xinyu city and to propose the intervention measures and the countermeasures to improve the prenatal diagnosis rate. Methods The incidence of birth defects in Xinyu City from 2001 to 2011 was retrospectively analyzed. The incidence of birth defects, incidence of birth defects, birth weight and birth weight and prenatal diagnosis were analyzed. Results The number of birth defects in 72514 cases of perinatal infants was 481 cases, the incidence of birth defects was 66.33 / 10000. With the increase of pregnant women ’s age, the incidence of birth defects in perinatal children increased (χ2 = 45.63, P <0.05) (RR = 4.59); the death rate of birth defects was higher than that of non-birth defects (RR = 16.21); Prenatal There were 151 cases of diagnosed birth defects (31.39%). Conclusion The incidence of birth defects in Xinyu City is high, the prenatal diagnosis rate is low, and it is imperative to improve the level of prenatal diagnosis.