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包括干扰素、肿瘤坏死因子及白细胞介素的细胞因子是一种正在发展的各种肽细胞调节因子家族。现在可获得天然的和重组的细胞因子用作抗肿瘤药剂,限制了细胞毒素化疗时的骨髓抑制作用。细胞因子的抗肿瘤作用可能是直接或间接的,这是通过破坏肿瘤的血液供给或刺激抗肿瘤的免疫应答来实现的。细胞因子在治疗癌症中可能还具有其他的作用,可起烈放射敏感剂、放射保护剂和癌基因表达调节剂
Cytokines including interferon, tumor necrosis factor, and interleukin are a family of various peptide cell regulators under development. Natural and recombinant cytokines are now available for use as anti-neoplastic agents, limiting the myelosuppressive effects of cytotoxic chemotherapy. The anti-tumor effects of cytokines may be direct or indirect, which is achieved by destroying the tumor’s blood supply or stimulating the anti-tumor immune response. Cytokines may also have other effects in the treatment of cancer, and may act as a potent radiation sensitizer, radioprotector, and oncogene expression modulator