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【目的】研究脑梗死患者踝肱指数（ankle ‐ brachial index ，ABI）特点及其与脑梗死发病的关系，探讨 ABI 对脑梗死患者神经功能的短期影响。【方法】选取2014年8月至2015年4月于本院神经内科住院的脑梗死患者100例，使用双向多谱勒血流测量仪检测患者 ABI ，分析患者 ABI 对脑梗死患者神经功能的短期影响；并分析患者早期神经功能恶化（END）发生的影响因素。【结果】100例患者，32例发生 END ，68例未发生 END 。单因素分析：早期发生 END 组患者 ABI ≤0．9的比例显著高于非 END 组（ P ＞0．05）；多因素 logis‐tic 回归分析：ABI ≤0．9与脑梗死患者 END 独立相关。【结论】ABI ≤0．9的脑梗死患者更容易在住院期间发生 END 。“,”Objective]To investigate the correlation between ankle‐brachial index (ABI) and early neuro‐logical deterioration (END) in patients with acute ischemic stroke and to discuss the short‐term impact of an‐kle‐brachial index (ABI) on the neurological function of patients with cerebral infarction .[Methods]A total of 100 cases of patients with acute ischemic stroke admitted to hospital from August 2014 ‐ April 2015 were en‐rolled in this study .ABI was determined according to the bidirectional Doppler blood flow measuring instru‐ment and the short‐term effects of ABI on the neurological function of patients with cerebral infarction were analyzed .The risk factors of END were analyzed .[Results] Out of the 100 patients ,32 cases had END (END group) and 68 did not have END (non‐END group) .Univariate analysis showed that the proportion of patients with ABI ≤ 0 .9 in the END group was significantly higher than in the non‐END group (53 .2 % vs .21 .3 % ;χ2= 8 .782 ,P = 0 .002) .Multivariable logistic regression analysis showed that ABI ≤ 0 .9 (odds ratio 2 .537 ,95 %confidence interval 1 .235 ~ 5 .032 ,P = 0 .008) was independently associated with END in patients with ischemic stroke after adjusting for confounding factors ,such as age ,sex ,baseline systolic blood pressure ,and smok‐ing .[Conclusion]Patients with cerebral infarction and ABI ≤ 0 .9 are more likely to suffer early neurologic de‐terioration (END) during hospitalization .