【摘 要】
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目的 观察帕米膦酸二钠联合化疗对骨转移癌的疗效及不良反应.方法 42例恶性肿瘤骨转移患者随机分为单用帕米膦酸二钠组20例(单用组)及帕米膦酸二钠联合化疗组22例(联合组),
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目的 观察帕米膦酸二钠联合化疗对骨转移癌的疗效及不良反应.方法 42例恶性肿瘤骨转移患者随机分为单用帕米膦酸二钠组20例(单用组)及帕米膦酸二钠联合化疗组22例(联合组),联合组患者采用帕米膦酸二钠联合如下方案:非小细胞肺癌用NP方案,小细胞肺癌用EP方案,乳腺癌用CAF方案,前列腺癌用FAM方案.结果 单用组镇痛有效率为65.0%,联合组为90.9%,两组差异有统计学意义(X2=4.17,P0.05).结论 帕米膦酸二钠联合化疗是治疗晚期恶性肿瘤骨转移的有效方案,不能耐受化疗的晚期肿瘤患者单用帕米膦酸二钠治疗,也可获得令人满意效果.
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