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探讨霉菌、幽门螺杆菌(Hp)单菌种感染和霉菌、Hp(双菌种)同时感染在胃癌及胃溃疡中的组织病理学变化、发病情况及意义。采用常规石蜡切片,HE染色和PAS、Giemsa特殊染色、免疫组织化学染色及PCR方法,对223例慢性浅表性胃炎、111例慢性萎缩性胃炎、116例胃溃疡、121例胃癌纤维胃镜活检标本进行回顾性研究。结果显示,慢性浅表性胃炎、慢性萎缩性胃炎未检出双菌种感染。胃溃疡双菌种感染11例,检出率9.5%;胃癌双菌种感染21例,检出率17.4%。双菌种感染在胃癌及胃溃疡中的发现,表明双菌种感染可能是导致胃溃疡、胃癌发生的又一致病因素。
To investigate the histopathological changes, pathogenesis and significance of simultaneous infection of mold, Helicobacter pylori (Hp) and mold and Hp (double strain) in gastric cancer and gastric ulcer. 223 cases of chronic superficial gastritis, 111 cases of chronic atrophic gastritis, 116 cases of gastric ulcer and 121 cases of gastroscopic biopsy specimens of gastric cancer were obtained by routine paraffin sections, HE staining and PAS, Giemsa special staining, immunohistochemical staining and PCR. Retrospective study. The results showed that chronic superficial gastritis, chronic atrophic gastritis were not detected double-strain infection. There were 11 cases of gastric ulcer infection, the detection rate was 9.5%; 21 cases of gastric bacterial infection, the detection rate was 17.4%. Two strains of bacteria found in gastric cancer and gastric ulcer, the discovery of double strains of infection may lead to gastric ulcer, gastric cancer is another risk factor.