The mechanism of propane ammoxidation has been investigatedby Monte Carlo approach With a model of two-activity-site of V/Sb catalystsand the consideration of compensation effect the performance of the V/Sbcatalysts was simulated as a funetion of V/(Sb+V)ratio The restilts showeda good agrecment with experimental data reported by others The mechanism of propane ammoxidation has been investigated by Monte Carlo approach with a model of two-activity-site of V / Sb catalysts and the consideration of compensation effect the performance of the V / Sbcatalysts was simulated as a funetion of V / (Sb + V) ratio The restilts showeda good agrecment with experimental data reported by others