我院自1979年起用环磷酰胺治疗流行性出血热,现就两年来治疗63例的临床观察结果报告如下。 63例中男45例,女18例,年龄15～69岁。用随机方法选出20例为对照组,该组只用一般综合治疗,包括利尿剂,止血剂、输液等;余43例为用药组,除一般综合治疗外,于临床上作出初步诊断后即用环磷酰胺,剂量为200毫克静脉推注,每日一次,疗程3天。根据使用环磷酰胺的不同时机,又分为发热期用药组、低血压期用药组和少尿期用药组。 Our hospital since 1979 with cyclophosphamide in the treatment of epidemic hemorrhagic fever, now two years to treat 63 cases of clinical observations are as follows. There were 45 males and 18 females in 63 cases, aged 15-69 years old. Twenty patients were selected as the control group by random method. The treatment group consisted of general treatment only, including diuretic, hemostatic agent and infusion. The remaining 43 patients were treated by combination therapy. After the initial diagnosis Cyclophosphamide, a dose of 200 mg intravenously, once daily for 3 days. According to the different timing of the use of cyclophosphamide, is divided into fever period medication group, hypotension period medication group and oliguria period medication group.