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樟柳碱(anisodime,简称AT_(-3))于1965年由中国医科院药物研究所从唐古特山莨菪中发现和分离的一种新生物碱,并已人工合成。1967年成都制药一厂从唐古特山莨菪生产阿托品的母液中提出AT_(-3),已成批生产。现就AT_(-3)的药理与临床应用作一简介。一、药物来源、化学结构、药理作用: (一)药物来源及化学结构:唐古特山莨菪(Scopolia tangutica,Anisadns tang-utica),俗名樟柳参,是茄科野生植物,生
Anisodimetin (AT_ (-3)) was discovered in 1965 by the Institute of Materia Medica, Chinese Academy of Medical Sciences from Anisodus tanguticus, and has been synthesized. In 1967, Chengdu Pharmaceutical Factory proposed AT _ (- 3) from the mother liquid of the production of atropine in Tangshan Anopheles, which has been mass-produced. Now on AT _ (- 3) pharmacology and clinical application for a brief introduction. First, the source of the drug, chemical structure, pharmacological effects: (A) the source and chemical structure of the drug: Tang Gu Te Anisadang (Anisadns tang-utica), commonly known as elm, is a Solanaceae wild plants,