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目的探讨1型糖尿病患儿情绪障碍与低血糖的关系。方法以儿童焦虑性情绪障碍筛查表(SCARED)及儿童抑郁障碍自评量表(DSRSC)为工具,评估57例1型糖尿病患儿的情绪状况,并回顾性分析患儿近2个月低血糖的发生情况。患儿SCARED或DSRSC评分超过相应诊断切点者,为情绪障碍组,余为情绪正常组。比较2组间发生低血糖的频率及严重程度,并分析1型糖尿病患儿情绪障碍与低血糖的关系。结果 57例患儿中28例存在情绪障碍,其中焦虑17例,抑郁11例。情绪障碍组与情绪正常组比较,严重低血糖及无症状低血糖的发生率显著增高(0.026vs0.080,0.056vs0.089,P<0.01,0.05);1型糖尿病患儿SCARED总评分、DSRSC总评分均与低血糖发生率呈正相关(Pa<0.05)。结论情绪障碍在1型糖尿病患儿中普遍存在,低血糖与儿童1型糖尿病情绪障碍相关,低血糖发生率高者易患情绪障碍。
Objective To investigate the relationship between mood disorders and hypoglycemia in children with type 1 diabetes mellitus. Methods Fifty-seven children with type 1 diabetes mellitus (T2DM) were assessed with SCARED and DSRSC as the tools, and the children’s changes in the past two months were retrospectively analyzed The occurrence of blood sugar. Children SCARED or DSRSC score more than the corresponding diagnosis of cut-off point for the emotional disorder group, the rest for the emotional group. The frequency and severity of hypoglycaemia were compared between the two groups and the relationship between mood disorders and hypoglycemia in children with type 1 diabetes mellitus was analyzed. Results Of the 57 children, 28 had mood disorders, including 17 anxiety cases and 11 depression cases. The incidence of severe hypoglycemia and asymptomatic hypoglycemia in mood disorder group was significantly higher than that in normal mood group (0.026vs0.080,0.056vs0.089, P <0.01,0.05); SCARED total score, DSRSC The total score was positively correlated with the incidence of hypoglycaemia (Pa <0.05). Conclusions Mood disorders are common in children with type 1 diabetes. Hypoglycemia is associated with mood disorders in children with type 1 diabetes. High incidence of hypoglycemia predisposes to emotional disorders.