在油田生产过程中，常常要使用多种有机化学药剂，加上其他环境条件（如温度、pH值、无机盐、溶解氧等）的适宜，往往会造成钻井液、完井液、压裂液、污水、注水的细菌污染，为了保证油田生产的正常进行，必须采取有效的措施控制细菌的危害。本文介绍和讨论了油田生产中的细菌危害及其杀菌技术，指出新型杀菌剂应向一剂多效方向发展。 In the oilfield production process, often use a variety of organic chemicals, coupled with other environmental conditions (such as temperature, pH, inorganic salts, dissolved oxygen, etc.) is appropriate, often resulting in drilling fluid, completion fluid, fracturing fluid , Sewage, water pollution, bacterial contamination, in order to ensure the normal oil field production, we must take effective measures to control bacterial hazards. This article describes and discusses the bacterial hazards and bactericidal technologies in oilfield production, and points out that the new type of bactericides should be developed in a more efficient way.