在欧洲和美国,Pycnogenol(?)是一种有专利权的饮食补充剂,系法国海岸松 Pinuspinaster Aiton 树皮提取物,主要活性成分是咖啡酸、桔酸、低聚原花青素、单体原花青素和前原花青素。药理试验、体内外动物试验和人体试验显示,海岸松树皮总提取物或部位在灌流器官中显示有很强的抗氧化活性,并证实它可以防止脂质过氧化、炎症和羟自由基引起的 DNA 损伤。此外,它还能通过减少 In Europe and the United States, Pycnogenol (?) is a patented dietary supplement, Pinus pinaster Aiton bark extract of France, the main active ingredient is caffeic acid, orange acid, oligomeric procyanidins, monomeric procyanidins and former Proantho Cyanidins. Pharmacological tests, animal studies in vivo and in vitro, and human trials have shown that the total extract or part of the coastal pine bark showed strong antioxidant activity in perfused organs and confirmed that it can prevent lipid peroxidation, inflammation, and hydroxyl radical-induced DNA damage. In addition, it can also reduce