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肾移植术后免疫抑制方案的选择对患者远期预后尤为重要,目前哺乳动物西罗莫司靶蛋白抑制药(m TORi)的使用越来越受到关注,但给药方案的选择、药物剂量、浓度控制范围等问题仍需要大量长期的临床研究。本文旨在通过总结国内外的相关研究,获得目前关于m TORi的研究现状,以便为患者提供更好的临床服务。
The choice of immunosuppressive regimen after renal transplantation is particularly important for the long-term prognosis of patients. At present, the use of mammalian sirolimus target protein inhibitor (mTOR) is receiving more and more attention. However, the choice of dosage regimen, dosage, Concentration control and other issues still require a large number of long-term clinical studies. The purpose of this paper is to summarize the relevant research at home and abroad, to obtain the current status of m TORi research in order to provide patients with better clinical services.