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目的观察Eales病患者血浆内皮素-1(Endothelin-1,ET-1)水平,探讨其与Eales病的关系。方法①将所有受试对象(包括Eales病患者及正常对照组)进行常规的全身检查及眼科检查②荧光素眼底血管造影结果结合眼底检查确定Eales病的分期。③内皮素-1的测定采用放射免疫法。结果①患病组ET-1平均值高于正常对照组(0.05,差别无统计学意义。③患病组中男性ET-1平均值比女性平均值含量高(<0.05),差别有统计学意义。④患病组ET-1与年龄成正相关。结论 Eales病的发生可能与血浆内皮素的水平增高有关,具体机制有待进一步探讨。“,”Objective The study observes Eales patients plasma Endothelin-1 level and explores their relationship to Eales disease.Methods ①Have al subjects (including Eales patients and normal matched control group) accept the conventional body checks and ophthalmic examination. ②FFA and ophthalmic examination determine the stage of Eales disease. ③Endothelin-1 tests use radioimmunoassay. Results ①The average of the patient group's ET-1 is higher than the control group ( 0.05. The dif erence is insignificant in statistical significance. ③The average of the males' ET-1 in the patient group is higher than the females' ( <0.05).The dif erence is significant in statistical significance.4. ET-1 is positive correlation with age in the patient group. Conclusion The level of plasma ET-1 is associated with the Eales disease.