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目的分析广州地区腹泻儿童A群轮状病毒(RV)抗原检测结果,探讨该地区A群RV感染与患儿年龄、性别及感染季节的相关性。方法选取腹泻儿童6 303例,检测其A群RV抗原并行统计学分析。结果 6 303例腹泻患儿中,RV感染2 489例,阳性率为39.49%。1~岁患儿RV感染率最高,阳性率为48.30%(占43.87%);其次是0~岁患儿,阳性率为45.59%(占24.95%);2~岁患儿阳性率为45.02%(占9.80%)。男性患儿RV阳性率为39.13%,女性患儿RV阳性率为39.96,差异无统计学意义(P>0.05)。10、11、12、1月是RV感染的发病高峰期,占84.44%。结论 A群轮状病毒感染与儿童腹泻存在密切关系,婴幼儿是A群RV的易感人群,A群RV感染无性别差异且高发于秋冬季节。
Objective To analyze the detection results of group A rotavirus (RV) antigen in children with diarrhea in Guangzhou and to explore the correlation between RV infection in group A and the age, sex and season of infection in this area. Methods A total of 6 303 children with diarrhea were enrolled in this study. A group of RV antigen was tested for statistical analysis. Results Among 6 303 children with diarrhea, 2 489 RV infections were detected, the positive rate was 39.49%. The prevalence of RV infection in children aged 1 ~ 4 was the highest (48.30% (43.87%), followed by children aged 0 ~ 45.59% (24.95%). The positive rate was 45.02% (9.80%). The positive rate of RV in male children was 39.13%, and the positive rate of RV in female children was 39.96, the difference was not statistically significant (P> 0.05). 10, 11, 12, January is the peak incidence of RV infection, accounting for 84.44%. Conclusion A group of rotavirus infection is closely related to childhood diarrhea. Infants and young children are susceptible to RV in group A. RV infection in group A has no gender difference and occurs in autumn and winter.