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目的分析非疫区布鲁氏菌病临床资料,查找误诊原因,为临床医生及早做出正确诊断提供依据。方法回顾性分析南京军区福州总院2010—2014年收治的布鲁氏菌病患者的临床资料。结果:3例病例纳入研究,男性2例,女性1例。平均38岁。3例患者均有牛羊等接触史。临床症状主要表现为发热、关节疼痛及乏力,淋巴结肿大是较突出的体征。实验室常规检查无特异性,布鲁氏菌血清凝集试验阳性率100.0%。误诊率为66.7%(2例)。3例病例经利福平和多西环素联合、长疗程治疗,均无复发。结论布鲁氏菌病临床症状不典型,易误诊,对发热原因不明患者,医务人员要警惕本病。
Objective To analyze the clinical data of brucellosis in non-endemic area and find out the causes of misdiagnosis so as to provide the basis for clinicians to make correct diagnosis as soon as possible. Methods The clinical data of brucellosis patients admitted to Fuzhou General Hospital of Nanjing Military Region from 2010 to 2014 were retrospectively analyzed. Results: Three cases were included in the study. There were 2 males and 1 females. Average 38 years old. 3 patients have history of exposure to cattle and sheep. The main clinical manifestations of fever, joint pain and fatigue, lymph node enlargement is more prominent signs. Laboratory routine examination non-specific, Brucella serum agglutination test positive rate of 100.0%. The misdiagnosis rate was 66.7% (two cases). 3 cases of the combination of rifampin and doxycycline, a long course of treatment, no recurrence. Conclusion Brucellosis clinical symptoms are not typical, easy to misdiagnosis, fever causes unknown patients, medical staff should be wary of the disease.