巨细胞病毒(CMV)感染可能引起移植肾功能和肾小球及肾间质的损伤,究竟肾脏损伤是感染还是移植肾耐受性降低的结果尚不清楚。作者研究了两侧CMV感染的婴儿肾组织。在光学和电子显微镜下都显示有间直性肾炎,而无肾小球病变。其冰冻组织用单克隆抗体经间接免疫荧光分析,证明大多数浸润细胞是T细胞(OKT+_3),其大多数和OKT_3起反应, Cytomegalovirus (CMV) infection may cause renal graft function and glomerular and renal interstitial damage, whether the kidney damage is infected or reduced renal transplant results are not clear. The authors studied infant kidney tissue infected with CMV on both sides. In the optical and electron microscopy showed ankylosis, but no glomerular lesions. The frozen tissue with monoclonal antibodies by indirect immunofluorescence analysis showed that most of the infiltrating cells are T cells (OKT + _3), most of them react with OKT_3,