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目的观察阿托伐他汀和辛伐他汀治疗高脂血症的临床效果。方法选取高脂血症患者130例,随机分为阿托伐他汀组和辛伐他汀组各65例,阿托伐他汀组予以阿托伐他汀治疗,辛伐他汀组给予辛伐他汀治疗,连续治疗8周后比较2组血脂水平及临床效果。结果治疗后2组各项指标均较治疗前明显改善,且阿托伐他汀组改善情况优于对照组,差异均有统计学意义(P<0.05)。阿托伐他汀组治疗总有效率高于辛伐他汀组,差异有统计学意义(P<0.05)。结论两者均有较好的降脂作用,相比之下,阿托伐他汀的降脂疗效优于辛伐他汀。
Objective To observe the clinical effects of atorvastatin and simvastatin in the treatment of hyperlipidemia. Methods A total of 130 patients with hyperlipidemia were randomly divided into atorvastatin group and simvastatin group, 65 cases in each group, atorvastatin group was treated with atorvastatin, simvastatin group was treated with simvastatin, continuous After 8 weeks of treatment, the blood lipid level and clinical effect of the two groups were compared. Results After treatment, the indexes in both groups were significantly improved compared with that before treatment, and the improvement in atorvastatin group was better than that in control group (P <0.05). The total effective rate of atorvastatin group was higher than that of simvastatin group, the difference was statistically significant (P <0.05). Conclusion Both have better lipid-lowering effect, compared with atorvastatin lipid-lowering effect is superior to simvastatin.