幽门螺杆菌(Hp)是全球范围内高感染率的慢性感染性致病菌。虽然儿童患消化性溃疡并不多见,但是Hp感染是儿童消化性溃疡的主要原因。Hp感染既会引起儿童疾病,也会带来经济社会的问题,目前对药物耐药性表现也越来越突出。该文针对儿童感染Hp的现状、相关性疾病的研究、基因研究、检测方法研究以及治疗等方面的研究进展予以综述。 Helicobacter pylori (Hp) is a chronic, highly contagious pathogen worldwide. Although children suffer from peptic ulcer is rare, but Hp infection is the main reason for children with peptic ulcer. Hp infection will not only cause diseases of children, but also bring about economic and social problems. At present, the performance of drug resistance is also more and more prominent. This article reviews the current status of Hp infection in children, related diseases, gene research, detection methods and treatment progress.