论文部分内容阅读
目的:了解四川省南部县食管癌筛查情况,为进一步提高食管癌及癌前病变早期检出率提供科学依据。方法:在四川省南部县食管癌高发区,采取整群随机抽样的方法选择部分自然村,以行政村为单元从公安部门获取人口学资料,完成全人口注册登记,以40~69岁居民作为筛查对象,进行内镜下碘染色及指示性活检筛查,并经病理学最终诊断确诊。结果:食管炎症及食管轻、中、重度异型增生的检出率分别为4.56%(639/14000)、6.09%(853/14000)、3.92%(549/14000)、0.74%(104/14000),食管浸润癌的检出率为0.31%(43/14000);各个级别食管病变的检出率男性均高于女性;各年龄段分析发现,轻、中度食管异型增生检出率随着年龄升高而增加,重度食管异型增生/原位癌在50岁~和65岁~两个年龄组高发。结论:在食管癌高发区人群中存在着相当数量的癌前病变患者,应对高危人群进行癌症综合知识宣传,提高防癌意识,做到食管癌的早发现、早诊断、早治疗。
Objective: To understand the esophageal cancer screening in southern county of Sichuan Province and provide scientific basis for further improving the early detection rate of esophageal cancer and precancerous lesions. Methods: In the high incidence area of esophageal cancer in southern county of Sichuan Province, part of the natural villages were selected by cluster random sampling method. Demographic data were obtained from the public security department with the administrative village as the unit. Registration of the entire population was completed. Residents aged 40-69 years Check the object for endoscopic iodine staining and biopsy screening and final diagnosis by pathology. Results: The detection rates of esophageal inflammation and mild, moderate and severe dysplasia of esophagus were 4.56% (639/14000), 6.09% (853/14000), 3.92% (549/14000) and 0.74% (104/14000) respectively, , The detection rate of esophageal cancer was 0.31% (43/14000). The detection rate of esophageal lesions in all ranks was higher than that in females. The analysis of each age group showed that the detection rate of light and moderate esophageal dysplasia varied with age Increased and increased, severe esophageal dysplasia / carcinoma in situ 50 years old ~ and 65 years old ~ two age groups. Conclusion: There are a large number of patients with precancerous lesions in the population with high risk of esophageal cancer. The high-risk population should be disseminated with comprehensive knowledge of cancer to raise awareness of cancer prevention so that early detection, early diagnosis and early treatment of esophageal cancer can be achieved.