利福平1965年问世以来,因其抗菌谱广,抗菌作用机制独特,口服易吸收,毒性小等优点而深受临床欢迎。利福平与药物配伍增多,药物的相互作用引起关注。利福平与口服抗凝剂、避孕药、糖皮质激素、奎尼丁、降糖药、巴比妥类及美敞痛的相互作用本刊已有报道。本文就近年文献中利福平与其它药物相互作用介绍如下。环孢霉素:kmghoff等报道1例尸体肾移植病人,术后按血药浓度使用环孢霉索,最初3周合用强 Since the advent of rifampicin in 1965, it has been widely welcomed by clinic because of its broad antibacterial spectrum, unique antibacterial mechanism, oral absorption and low toxicity. Rifampicin and drug compatibility increased, drug interactions cause concern. The rifampicin and oral anticoagulants, contraceptives, glucocorticoids, quinidine, hypoglycemic agents, barbiturates and the United States and the role of broad-leaved pain has been reported. This article on the recent literature rifampicin and other drug interactions are as follows. Cyclosporine: kmghoff et al reported 1 case of cadaveric kidney transplant patients, according to the blood concentration of cyclosporine after surgery, the first 3 weeks combined with strong