近 2 0年来卵巢上皮癌的疗效有了明显改善 ,这与积极的肿瘤细胞减灭术和顺铂联合化疗的进展密不可分。卵巢癌的一线化疗历经烷化剂、顺铂及顺铂联合化疗和紫杉醇顺铂联合化疗 3个时期 ,但晚期癌的 5年存活率仍为2 0 % [1] 。至今尚不能确定铂类单药及其联合、紫杉醇铂类联合哪 The efficacy of ovarian epithelial cancer has been significantly improved over the past 20 years, which is closely related to the progress of active cytoreductive surgery and cisplatin combined with chemotherapy. The first-line treatment of ovarian cancer after alkylating agents, cisplatin and cisplatin combination chemotherapy and paclitaxel cisplatin combined with chemotherapy in three periods, but the 5-year survival rate of advanced cancer is still 20% [1]. To date, it has not been confirmed which single platinum platinum and its combination, paclitaxel and platinum combined