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目的探讨大学生运动与非酒精性脂肪肝的相关性,为预防非酒精性脂肪肝(NAFLD)的发生提供依据。方法选取秦皇岛市425名在校大学生,根据运动情况分为A组(每周锻炼4～7d)、B组(每周锻炼1～3d)和C组(不参加体育锻炼)。测量身高、体重、腰围(WC)和血压,检测空腹血糖(FPG)、血三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、谷丙转氨酶(ALT)、谷草转氨酶(AST)和血清真胰岛素(TI)水平,计算胰岛素抵抗指数(HOMA-IR),并行肝脏超声检查。结果 C组BMI,WC,TI和HOMA-IR水平高于A组和B组,C组HDL-C水平低于B组(P<0.05)。3组间比较,C组代谢综合征和NAFLD检出率明显升高(P<0.05)。Logistic回归分析显示,不参加体育锻炼是大学生代谢综合征的独立危险因素(OR=5.807,P=0.015);腹型肥胖(OR=7.476,P=0.000)和不参加体育锻炼(OR=2.614,P=0.031)是大学生NAFLD的独立危险因素。结论不参加体育锻炼是大学生非酒精性脂肪肝和代谢综合征的独立危险因素。应早期指导大学生合理运动,预防非酒精性脂肪肝和代谢综合征的发生。
Objective To explore the correlation between college students’ exercise and non-alcoholic fatty liver and provide basis for prevention of non-alcoholic fatty liver disease (NAFLD). Methods A total of 425 undergraduates from Qinhuangdao City were enrolled in this study. They were divided into group A (4-7 days per week), group B (1-3 days per week) and group C (no physical activity). Body weight, waist circumference (WC) and blood pressure were measured. Fasting plasma glucose (FPG), triglyceride (TG), high density lipoprotein cholesterol (HDL-C), alanine aminotransferase (ALT) and aspartate aminotransferase (AST) And serum true insulin (TI) levels were calculated insulin resistance index (HOMA-IR), parallel liver ultrasound. Results The levels of BMI, WC, TI and HOMA-IR in group C were higher than those in groups A and B, while the levels of HDL-C in group C were lower than those in group B (P <0.05). Among the three groups, the detection rate of metabolic syndrome and NAFLD in group C was significantly higher (P <0.05). Logistic regression analysis showed that physical exercise was an independent risk factor for metabolic syndrome in college students (OR = 5.807, P = 0.015); abdominal obesity (OR = 7.476, P = 0.000) 0.031) is an independent risk factor for college students NAFLD. Conclusion Non-physical exercise is an independent risk factor for non-alcoholic fatty liver disease and metabolic syndrome in college students. Should guide the reasonable exercise of college students early to prevent the occurrence of non-alcoholic fatty liver and metabolic syndrome.