Refsum 综合征又称遗传性共济失调性多发神经炎,至今国外文献记载约60余例,国内尚未见报道。特将我们发现的1例报告如下。林××男,40岁,已婚。进行性四肢无力,发麻及不自主抖动近2个月,于1979年3月13日入院。1979年1月中旬渐感双下肢发麻无力,活动不灵活,每步行10～20分钟,即感极度疲惫,需休息半小时后方可再走。继而于站立或步 Refsum syndrome, also known as genetic ataxia polyneuritis, so far about 60 foreign literature records, has not been reported in China. We will find one special report is as follows. Lin XX male, 40 years old, married. Progressive limb weakness, numbness and involuntary jitter nearly 2 months, on March 13, 1979 admission. In mid-January 1979 gradually lower limbs feel numb, activity is not flexible, every walk 10 to 20 minutes, that is extremely tired, need to rest for half an hour before they go. Then stand or step