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观察依替米星 (商品名 :爱大 )对下呼吸道细菌感染的临床疗效及不良反应。 2 0例下呼吸道感染病人 ,其中急性支气管炎 1例 ,肺炎 8例 ,慢性支气管炎伴感染 5例 ,支气管扩张 6例。病情轻度 3例 ,中度 14例 ,重度 3例。硫酸依替米星 10 0 mg+0 .9%生理盐水静脉滴注 ,q12 h,疗程 3～ 12 d,有效率 90 .0 % (18/2 0 ) ,其中 3例重症感染 (2例为金葡球菌感染 )需联合其他抗生素治疗 ;细菌清除率 78.6 % (11/14)。除 2例有轻微腹泻、腹胀外 ,未发现其它不良反应及耳、肾毒性。提示硫酸依替米星用于治疗下呼吸道细菌感染有效 ,不良反应轻微。
To observe the clinical efficacy and adverse reactions of etimicin (trade name: Ai Da) on lower respiratory tract bacterial infections. 20 cases of lower respiratory tract infection patients, including 1 case of acute bronchitis, 8 cases of pneumonia, chronic bronchitis with infection in 5 cases, bronchiectasis in 6 cases. Mild mild in 3 cases, moderate in 14 cases, severe in 3 cases. Etimicin sulfate 10 0 mg +0. 9% saline infusion, q12 h, the course of 3 ~ 12 d, the effective rate was 90.0% (18/2), of which 3 cases of severe infection (2 were Staphylococcus aureus infection) should be combined with other antibiotics; bacterial clearance rate of 78.6% (11/14). In addition to 2 cases of mild diarrhea, abdominal distension, no other adverse reactions and ear, nephrotoxicity was found. Tip etimicin sulfate for the treatment of lower respiratory tract bacterial infections effective, minor adverse reactions.