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目的:研究口服补液盐(ORS)在儿童体位性低血压中的应用价值。方法:选取我院诊断为体位性低血压患儿88例,根据治疗方式分为ORS组45例和传统治疗组43例,观察并比较两组患儿治疗前后直立倾斜试验(HUTT)阳性率、血压、相关症状发生率等。结果:ORS组治疗后HUTT阳性率6.67%,低于传统治疗组的23.26%(P<0.05)。ORS组治疗后HUTT-3 min和HUTT-7 min时的收缩压(SBP)、舒张压(DBP)均高于治疗前(P均<0.05),且SBP高于传统治疗组(P<0.05)。传统治疗组治疗后HUTT-3 min和HUTT-7 min时的DBP均高于治疗前(P均<0.05),HUTT-3 min时的SBP高于治疗前(P<0.05),但HUTT-7 min时的SBP与治疗前比较差异无统计学意义(P>0.05)。ORS组头晕、心悸、乏力、视物模糊发生率分别为8.89%、6.67%、13.33%、8.89%,均低于传统治疗组的27.91%、25.58%、34.88%、30.23%(P均<0.05)。结论:ORS治疗儿童体位性低血压可迅速有效地升高血压,尤其是SBP,减少头晕等的发生,其机制可能与提高患儿对体位改变的耐受力有关。
Objective: To study the value of oral rehydration salts (ORS) in orthostatic hypotension in children. Methods: 88 cases diagnosed as orthostatic hypotension in our hospital were divided into 45 cases of ORS group and 43 cases of traditional treatment group according to the way of treatment. The positive rate of upright tilt test (HUTT) before and after treatment in both groups was observed and compared. Blood pressure, the incidence of related symptoms. Results: The positive rate of HUTT in ORS group was 6.67%, which was lower than 23.26% (P <0.05) of the traditional treatment group. The SBP and DBP of HUTT-3 min and HUTT-7 min after treatment in ORS group were significantly higher than those before treatment (all P <0.05), and SBP was higher than that in the traditional treatment group (P <0.05) . The DBP of HUTT-3 min and HUTT-7 min after treatment in the traditional treatment group were significantly higher than those before treatment (all P <0.05). The SBP in HUTT-3 min was higher than that before treatment (P <0.05) There was no significant difference in SBP between before and after treatment (P> 0.05). The incidences of dizziness, palpitation, fatigue and blurred vision were 8.89%, 6.67%, 13.33% and 8.89% in the ORS group, respectively, which were all lower than those in the traditional treatment group (27.91%, 25.58%, 34.88%, 30.23% ). Conclusion: ORS treatment of orthostatic hypotension in children can quickly and effectively increase blood pressure, especially SBP, reduce the incidence of dizziness, and its mechanism may be related to improving children’s tolerance to body position changes.