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目的：探讨实验兔膝关节软骨生物力学性质是否随深度变化。方法：应用微应力实验装置分别测定不同层厚兔膝关节软骨的生物力学性质：整体模数（ａｇｇｒｅｇａｔｅｍｏｄｕｌｕｓ，ＨＡ）、普爱松模数（Ｐｏｉｓｓｏｎｓｒａｔｉｏ，υｓ）、剪切弹性模量（ｓｈｅａｒｍｏｄｕｌｕｓ，μ）及通透性（ｐｅｒｍｅａｂｉｌｉｔｙ，Ｋ）的变化。结果：表层软骨ＨＡ、μ明显低于深层软骨（Ｐ＜０．０５）；而软骨的通透性从表层往深部逐渐增高（Ｐ＜０．０５）。结论：关节软骨的生物力学性质随深度变化。表层关节软骨对维持软骨生物力学性质是极其重要的，任何该区域性质的变化将明显地影响软骨的生物力学性质乃至正常的关节功能。
Objective: To investigate whether the biomechanical properties of knee cartilage of experimental rabbits vary with depth. Methods: The biomechanical properties of knee cartilage of rabbits with different layer thickness were measured by micro-stress device: the total modulus (HA), Poisson’s modulus (υs), shear modulus (Shearmodulus, μ) and permeability (permeability, K) changes. Results: The surface cartilage HA and μ were significantly lower than that of the deep cartilage (P <0.05). The cartilage permeability increased gradually from the surface to the deep (P <0.05). Conclusions: The biomechanical properties of articular cartilage vary with depth. Superficial articular cartilage is extremely important in maintaining cartilage biomechanical properties, and any change in the properties of this area will significantly affect the cartilage biomechanical properties and even normal joint function.