应用卡巴拉汀治疗轻到中重度阿尔茨海默病患者52周有效性研究(译文)

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卡巴拉汀酒石酸盐(ENA713,艾斯能)是具有中枢活性的胆碱酯酶抑制剂.通过为期26周、双盲、安慰剂对照研究后,又进行了为期26周的开放标记扩展临床研究,以评估其治疗轻到中重度阿尔茨海默病的有效性.结果表明,服用卡巴拉汀6~12 mg/d共52周的患者,认知功能明显好于以前服用安慰剂者.
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