Using secondary spinel standard method, we have measured precisely the compositions of spinels of amphibole-bearing mantle peridotite xenoliths from Nüshan in eastern China, and calculated the mantle oxygen fugacities recorded by the xenoliths. Results indicate that the mantle metasomatism for forming amphiboles in Nüshan region of Anhui has resulted in the decrease of mantle redox, which is in contrast with theoretical estimation and previous research results from other areas around the world. Combining with related studies on the mantle of eastern China, we give a reasonable explanation to the 'new finding' and further elucidate the compositions and nature of mantle fluids in eastern China.