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维持正常人血糖的平稳,需要先天的、后天的多种因素的参与:遗传基因、酶、胰岛素等,其中尽管各因素有多大比例参与,但是通常葡萄糖运输足以有效地允许细胞内和细胞外葡萄糖浓度的快速平衡~([1-2])。悉知胰岛素在其中伴演着十分重要的角色,但还有一个就是ATP敏感K~+通道(K~+-ATP通道)。1 K_(ATP)通道存在于β细胞膜上,是由两类受体组成:一个是高亲和性磺脲类受体~((SUR1))和一个内向校正的K~+通道
Maintaining a steady blood glucose in normal humans requires the involvement of a number of innate, acquired factors: genes, enzymes, insulin and the like, although glucose transport is generally sufficient to effectively allow both intracellular and extracellular glucose Rapid balance of concentration ~ ([1-2]). It is known that insulin plays an important role in it, but there is also an ATP-sensitive K + channel (K + -ATP channel). 1 K ATP channel exists in the beta cell membrane and is composed of two types of receptors: one is the high affinity sulfonylurea receptor ~ ((SUR1)) and an inwardly corrected K ~ + channel