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目的：探讨喜炎平联合蒲地蓝治疗带状疱疹的效果和对细胞免疫功能的影响。方法选择收治带状疱疹患者66例，随机分为治疗组和对照组，治疗组给予喜炎平注射液50 mg加入250 mL生理盐水中，静滴，1次/d，共滴注7 d；蒲地蓝消炎口服液，10 mL/次，3次/d，共用药7 d。对照组给予膦甲酸钠氯化钠注射液3.0，1次/d，共滴注7 d。伐昔洛韦口服0.3，2次/d，弥可保0.5 mg，3次/d，观察2组治疗效果及止疱、结痂、脱痂、疼痛缓解的时间、睡眠状况、生活质量改善状况等，并采用流式细胞仪检测治疗前，治疗10 d后患者外周血T细胞亚群改变情况。结果治疗组治疗总有效率明显高于对照组；治疗组止疱、结痂、脱痂、疼痛缓解时间明显短于对照组；治疗组睡眠质量评分和生活质量评分高于对照组；治疗组患者治疗后CD3、CD4、CD8、CD4/CD8明显高于对照组。结论该法治疗带状疱疹有效率高、症状缓解快，并且可以有效调节T细胞亚群功能，增强患者免疫防护。“,”Objective To investigate the clinical effect and cell immune function of combination of Xiyan-ping and pudilan oral liquid in the treatment of herpes zoster. Methods Sixty-six cases of herpes zoster were di-vided into treatment group and control group randomly. The treatment group were given Xiyanping 50 mg per day by intravenous drip and pudilan oral liquid 10 mL three times daily for one week. The control group were given foscarnet 3.0 per day by intravenous drip and valaciclovir 0.3 two times daily, methycobal 0.5 mg three times daily for one week. To investigate the clinical effect and the time of stopping vesication, incrustation and decrusta-tion, sleep quality score and routine life quality, and to detect the T cell subset changes of the patients at the before treatment and after the treatment of ten days circumstance. Results The total effective rate of the treatment group was signiifcantly better than the control group. Conclusion This treatment of herpes zoster has a high efifcient, and can effectively regulate T cell subgroup function, enhance patients’ immune protection.