新生儿坏死性小肠结肠炎(necrotizing enterocolitis,NEC)是新生儿期一种较常见的消化系统疾病,也是导致新生儿肠穿孔及全身炎症反应综合征(systemic inflammatory response,SIRS)的主要原因之一,已成为新生儿死亡的重要病因。近20年来,随着早产儿存活率的提高,NEC发病率明显增加。不同国家、不同临床中心报道的NEC发病率各不相同。一般认为,NEC在新生儿重 Necrotizing necrotizing enterocolitis (NEC) is one of the more common digestive diseases in the neonatal period, which is also one of the main causes of intestinal perforation and systemic inflammatory response syndrome (SIRS) in neonates. , Has become an important cause of neonatal death. In the past 20 years, with the survival rate of premature infants increased, the incidence of NEC increased significantly. Different countries, different clinical centers reported the incidence of NEC vary. It is generally believed that NEC is heavy in newborns