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目的探讨动脉灌注化疗提高局部晚期直肠癌放射治疗疗效。方法56例局部晚期直肠癌随机分为动脉灌注化疗配合放射治疗组(综合组)28例,单纯放射治疗组(单放组)28例。动脉灌注化疗采取经肠系膜下动脉和髂内动脉灌注,放射治疗采用60Co照射。结果综合组有效率为85.7%,单放组有效率为57%(P<0.01)。结论放疗辅以动脉灌注化疗为局部晚期直肠癌的有效治疗方法。
Objective To investigate the efficacy of arterial infusion chemotherapy in the treatment of locally advanced rectal cancer. Methods Fifty-six patients with locally advanced rectal cancer were randomly divided into two groups: arterial infusion chemotherapy combined with radiation therapy group (comprehensive group) 28 cases, and radiotherapy alone group (single release group) 28 cases. Arterial infusion chemotherapy was performed through the inferior mesenteric artery and internal iliac artery. Radiotherapy was performed with 60Co irradiation. Results The effective rate was 85.7% in the comprehensive group and 57% in the radiotherapy group (P<0.01). Conclusion Radiotherapy combined with arterial infusion chemotherapy is an effective treatment for locally advanced rectal cancer.