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目的评价二维和彩色多普勒对颈动脉狭窄诊断及疗效判断的价值。方法用球囊加血管环扎法建立犬颅外段颈动脉狭窄模型,对其在经皮血管成形术(PTAS)治疗前及治疗后即刻、1月、2月、3月行高频超声动态观察,并与同期DSA检查及病理检查结果比较。结果①超声能准确确定颈动脉狭窄部位、范围、程度以及血流动力学改变。②PTAS治疗后,超声能观察支架位置形态,支架处管腔内径,彩色及频谱多普勒能观察支架内部及近远段血管内血流动力学改变,并根据血流动力学改变判断再狭窄的发生和狭窄程度。③PTAS术后,超声不能清楚显示支架内壁及腔内结构,支架内血流信号显示不丰满。结论超声对颈动脉狭窄诊断及疗效判断有重要价值,是临床首选的无创检查方法。
Objective To evaluate the value of two-dimensional and color Doppler in diagnosing carotid artery stenosis and judging its curative effect. Methods The canine extracranial carotid artery stenosis model was established by balloon and cerclage method. Before and after treatment of percutaneous transluminal angioplasty (PTAS), the model of high frequency ultrasound was established in January, February and March. Observed, and with the same period of DSA examination and pathological examination results. Results ① Ultrasound can accurately determine the location of the carotid artery stenosis, extent, and hemodynamic changes. ②PTAS treatment, ultrasound can observe the position and shape of the stent, stent diameter at the lumen, color and spectral Doppler can be observed inside and near the stent vascular hemodynamic changes, and to determine the changes in hemodynamic restenosis Occurrence and stenosis. ③ PTAS surgery, ultrasound can not clearly show the stent wall and the structure of the lumen, stent blood flow signal shows not full. Conclusion Ultrasound has important value in the diagnosis and treatment of carotid artery stenosis and is the first choice of non-invasive clinical examination.