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目的探讨前降钙素(PCT)、CRP在细菌性脑膜炎与病毒性脑炎早期鉴别诊断中的作用。方法采用双抗体夹心免疫荧光法测定菌脑48例,病脑50例,血清及脑脊液中PCT含量,血CRP含量采用ELISA法测定。结果与病脑组比较,菌脑组血清PCT和CRP含量明显升高,经统计学处理P<0.01,两组差异有显著性。结论PCT是早期鉴别菌脑与病脑的灵敏指标。
Objective To investigate the role of procalcitonin (PCT) and CRP in the early differential diagnosis of bacterial meningitis and viral encephalitis. Methods 48 cases of cerebrum and 50 cases of pathological brain were determined by double antibody sandwich immunofluorescence method. The contents of PCT and CRP in serum and cerebrospinal fluid were measured by ELISA. Results Compared with diseased brain group, the contents of serum PCT and CRP in the cerebrum group were significantly increased. After statistical analysis, P <0.01, there was significant difference between the two groups. Conclusion PCT is a sensitive indicator of early identification of brain and brain disease.