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目的:探究哌地尔在老年前列腺增生(BPH)治疗中的临床价值。方法:选取2014年1月-2015年3月我院收治确诊前列腺增生的老年患者76例,随机划分为观察组和对照组,各38例,对照组给予盐酸坦索罗辛治疗,观察组给予哌地尔治疗,对比两组排尿症状评分(USS)、生存质量评定(QOL)、平均尿流率(Qave)、国际前列腺症状评分(IPSS)、血压、心率、心电图、血常规等指标。结果:两组USS、IPSS、QOL、Qave、Qmax指标评分治疗前后组内比较,差异具有统计学意义(P<0.05或P<0.01);组间治疗后Qmax指标比较,差异具有统计学意义(P<0.05);两组治疗前后血压、心电图、心率、尿常规等指标均无无统计学意义(P>0.05);观察组不良反应发生率8.33%明显优于对照组13.89%,差异具有统计学意义(P<0.05)结论:盐酸坦索罗辛、哌地尔均可有效缓解BPH症状,而哌地尔增加Qmax效果更加显著,可有效减少不良反应,具有较高的临床价值。
Objective: To investigate the clinical value of pipilil in the treatment of benign prostatic hyperplasia (BPH). Methods: A total of 76 elderly patients admitted to our hospital from January 2014 to March 2015 were randomly divided into observation group and control group, 38 cases in each group. The control group was treated with tamsulosin hydrochloride. The observation group was given The effects of USP, QOL, Qave, IPSS, blood pressure, heart rate, electrocardiogram and blood routine were compared between the two groups. Results: The scores of USS, IPSS, QOL, Qave and Qmax in two groups before and after treatment were significantly different (P <0.05 or P <0.01). There was significant difference in Qmax between the two groups after treatment P <0.05). Before and after treatment, blood pressure, electrocardiogram, heart rate, urine routine and other indexes had no statistical significance (P> 0.05). The incidence of adverse reactions in the observation group was significantly higher than that of the control group (8.33%, 13.89% Significance (P <0.05) Conclusion: Tamsulosin hydrochloride and pipodil can effectively relieve the symptoms of BPH. However, the effect of Pipilil on Qmax is more significant, which can effectively reduce adverse reactions and has high clinical value.