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目的评价初筛献血者ALT活性的应用效果。方法比较2个采血点同一时期分别采用ALT初筛的复检不合格率和不采用初筛的不合格率,比较ALT干式生化法和速率法结果的相关性,并探讨各影响因素与ALT之间的关系。结果采用ALT初筛献血者复检不合格率明显低于不进行初筛者(P<0.05),干式生化法和速率法结果具有较好的相关性(r=0.993,P<0.05),体质指数(BMI)、饮酒、睡眠、运动、糖尿病史、肝脏病史是ALT活性独立影响因素(P<0.05)。结论 ALT初筛可大幅度减少复检血液ALT不合格报废率。
Objective To evaluate the effect of ALT activity in primary screening blood donors. Methods The differences of ALT screening rate and non-screening rate of ALT screening were compared between the two blood collection points in the same period. The correlation between ALT dry rate and rate method was compared. The relationship between ALT The relationship between. Results The unqualified rate of ALT screening test was significantly lower than that of no screening (P <0.05). There was a good correlation between dry biochemical method and rate test (r = 0.993, P <0.05) Body mass index (BMI), alcohol consumption, sleep, exercise, diabetes mellitus and history of liver disease were independent factors of ALT activity (P <0.05). Conclusion ALT screening can significantly reduce the retest blood ALT failed rejection rate.