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前列腺素(PG)与白三烯(LT)是花生四烯酸(AA)分别经环氧酶和5-脂氧酶代谢途径形成的代谢物,具有重要生物活性,已引起了人们广泛重视。由于AA代谢物复杂多样,因此有效的分离手段对研究这类物质十分重要。虽然高效液相(HPLC)和气质联用(GC-MS)等己用于PG及LT的分离检测,但由于这类仪器的来源_及价格,仍不能为一般实验室所具备。因此寻找简便和有效
Prostaglandins (PGs) and leukotrienes (LTs) are metabolites formed by arachidonic acid (AA) via the metabolic pathways of cyclooxygenase and 5-lipoxygenase, respectively, and have important biological activities. It has attracted widespread attention. Because AA metabolites are complex and diverse, effective methods of separation are important for studying such substances. Although high-performance liquid chromatography (HPLC) and gas chromatography mass spectrometry (GC-MS) have been used for the separation and detection of PG and LT, due to the sources and the prices of such instruments, they are still not available to general laboratories. So looking for simplicity and effectiveness