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涎腺功能低下(SGH)对口腔伤口愈合的影响尚不完全明确,本文研究了SGH鼠模型的拔牙刨愈合情况。80只雄性Sprague-Dawley鼠,2月龄,体重200g,随机分为实验组和对照组。实验组行双侧颌下腺、舌下腺切除术,结扎腮腺导管。对照组行假性手术,将同部位腺体完全暴露后再缝合。两组动物于术后两周均拔除上颌左侧第一磨牙。每组于术后0,1,3,5,7,10,14,21天各处死5只,做大体观察后将标本块置18％EDTA溶液内脱钙两周,然后制片用光学显微镜观察。
The effect of salivary gland dysfunction (SGH) on the healing of oral wounds is not yet completely understood. In this paper, the healing condition of tooth extraction in SGH mice was studied. Eighty male Sprague-Dawley rats, 2 months old and weighing 200 g, were randomly divided into experimental and control groups. Experimental group bilateral submandibular gland, sublingual gland resection, parotid duct ligation. Control group of pseudo-surgery, the same part of the gland after complete exposure and then suture. Two groups of animals were removed first maxillary left first molars two weeks after surgery. Five rabbits were sacrificed at 0,1,3,5,7,10,14,21 days after operation. After gross observation, the specimens were decalcified in 18% EDTA for two weeks, and then photographed by light microscopy Observed.