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目的:观察鼻塞持续气道正压通气(NCPAP)联合清开灵治疗婴幼儿重症肺炎的疗效。方法:将60例婴幼儿重症肺炎患儿随机分为两组,每组30例,两组基础治疗相同,治疗组采用清开灵联合鼻塞CPAP治疗,观察组采用低流量给氧治疗,比较分析两组病例的临床资料。结果:治疗组治疗1h后患儿喘憋、紫绀、三凹征及呼吸困难缓解,心率、呼吸、氧饱和度、PaO2、PaCO2改善明显优于对照组(P<0.01);治疗组临床表现消失时间明显短于对照组,差异有显著性(P<0.01)。结论:鼻塞持续气道正压通气(NCPAP)联合清开灵治疗婴幼儿重症肺炎能有效改善患儿肺氧合和通气功能,缩短病程,降低病死率,设备简便,操作容易,且并发症少。
Objective: To observe the curative effect of nasal continuous positive airway pressure (NCPAP) combined with Qingkailing in the treatment of infantile severe pneumonia. Methods: Sixty infants with severe pneumonia were randomly divided into two groups (n = 30 in each group). The two groups had the same basic treatment. The treatment group was treated with Qingkailing combined with nasal CPAP. The observation group was given low-flow oxygen therapy. Clinical data of two groups of patients. Results: In the treatment group, wheezing, cyanosis, trigeminal levitation and dyspnea were relieved in 1 h after treatment, and the improvement of heart rate, respiration, oxygen saturation, PaO2 and PaCO2 were significantly better than those of the control group (P <0.01) Time was significantly shorter than the control group, the difference was significant (P <0.01). Conclusion: Nasal continuous positive airway pressure (NCPAP) and Qingkailing treatment of infantile severe pneumonia can effectively improve pulmonary oxygenation and ventilation in children, shorten the course of disease, reduce mortality, the device is simple, easy to operate, and the complication of less .