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本文研究了5例基底细胞癌(BCC)肌上皮分化的形态学、免疫组化及病理学特征。临床资料:3男2女,年龄43~65岁,皮损为淡褐色光滑坚实的结节,直径0.5~1.2cm,均局限在面部。切除标本福尔马林固定,石蜡包埋,HE、PAS(未经淀粉酶消化)及阿新蓝染色。免疫组化采用ABC技术,用抗CAM5.2、角蛋白AE-1/AE-3、癌胚抗原(CEA)、S100蛋白、肌肉特异性的肌动蛋白、结蛋白(desmin)、波状纤维蛋白(vimentin)和神经胶质原纤维酸性蛋白(GFAR)抗体染色。
This article studied the morphological, immunohistochemical and pathological features of myoepithelial differentiation in 5 cases of basal cell carcinoma (BCC). Clinical data: 3 males and 2 females, aged 43 to 65 years old. The lesions were light brown, smooth and firm nodules with diameters of 0.5 to 1.2 cm, and were confined to the face. The specimens were fixed in formalin, paraffin-embedded, HE, PAS (without amylase digestion) and alcian blue staining. Immunohistochemistry using ABC technique with anti-CAM5.2, keratin AE-1/AE-3, carcinoembryonic antigen (CEA), S100 protein, muscle-specific actin, desmin, wavy fibrin (vimentin) and glial fibrillary acidic protein (GFAR) antibody staining.