论文部分内容阅读
目的观察经微导管超选择小脑前下动脉尿激酶溶栓治疗血管性突发性耳聋之疗效。方法 74例血管性突发性耳聋患者随机接受动脉或静脉溶栓治疗,手术后辅助低分子肝素(0.40 ml)和阿司匹林(100 mg)抗血小板聚集,分别于治疗后第1、3、6和10天复查电测听,以判定疗效。结果治疗第10天时,动脉溶栓治疗组患者治疗总有效率达84.21%(32/38),静脉溶栓治疗组为58.33%(21/36),两组比较差异有统计学意义(x~2=6.091,P=0.014)。两组溶栓治疗后不同观察时间点电测听结果比较,动脉溶栓治疗组显著优于静脉溶栓治疗组,差异有统计学意义(均P<0.01)。结论超选择经动脉予以尿激酶可能是治疗血管性突发性耳聋的有效方法。
Objective To observe the effect of microcatheter superselective anterior urokinase thrombolytic therapy for sudden vascular deafness. Methods A total of 74 patients with sudden vascular deafness were treated with arterial or venous thrombolysis. After operation, low molecular weight heparin (0.40 ml) and aspirin (100 mg) 10 days to review the electrical test to determine the efficacy. Results At the 10th day of treatment, the total effective rate was 84.21% (32/38) in the arterial thrombolytic therapy group and 58.33% (21/36) in the intravenous thrombolytic therapy group, the difference between the two groups was statistically significant (x ~ 2 = 6.091, P = 0.014). In the two groups after thrombolytic therapy at different time points compared with the results of electrical audiometry, arterial thrombolysis group was significantly better than intravenous thrombolytic therapy group, the difference was statistically significant (P <0.01). Conclusion Superselective administration of urokinase via the artery may be an effective method for the treatment of sudden vascular deafness.