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病例介绍例1:周,16岁,男。潮热、盗汗、消瘦三月。查体:T38℃,心肺(一),腹膨隆柔韧,有数个肿块压痛,肝脾(一)腹水卅。Hb8.0/dl,ESR114mm/h,总蛋白5.2g/dl,肾功正常。x线检查:左肺结核、腹腔结核。腹水渗液,经草兰氏及抗酸染色查菌(一)。日服RFP0.45g、INH0.3g,SM0.375g肌注日2次。14天后感肝区痛、恶心呕吐,无食欲。肝大1cm,质软触痛。黄疸指数8u、ZnTT18u、碘试验(+)胆红素1.1mg/dl,GPT76u(正常27u),AKP、HbsAg、肾功正常。WBC8500,N70％,E5％。停服RFP,加服肌苷、强的松,14天后症状消失,肝功正常。例2:肖,48岁,女。潮热,腹胀,纳差、力日服INH0.3g,RTP0.6g,肌注SM0.75g
Case description Example 1: week, 16 years old, male. Hot flashes, night sweats, weight loss March. Physical examination: T38 ℃, cardiopulmonary (A), abdominal bulging flexible, several lumps tenderness, liver and spleen (a) ascites. Hb8.0 / dl, ESR114mm / h, total protein 5.2g / dl, normal renal function. X-ray examination: left pulmonary tuberculosis, abdominal tuberculosis. Ascites exudate, the grass Lancaster and acid-fast bacteria (1). Japanese service RFP0.45g, INH0.3g, SM0.375g intramuscular injection 2 times. 14 days after the liver area pain, nausea and vomiting, no appetite. Liver 1cm, soft tenderness. Jaundice index 8u, ZnTT18u, iodine test (+) bilirubin 1.1mg / dl, GPT76u (normal 27u), AKP, HbsAg, normal renal function. WBC8500, N70%, E5%. Stop taking RFP, plus service inosine, prednisone, 14 days after the symptoms disappeared, normal liver function. Example 2: Xiao, 48 years old, female. Hot flashes, abdominal distension, anorexia, force daily INH0.3g, RTP0.6g, intramuscular SM0.75g