炎症是组织对损伤因子所发生的防御反应,以毛细血管扩张和炎症细胞渗出为特征,其在疾病的发生、发展过程中发挥重要作用。抑制炎症反应达到改善全身情况,减少器官组织损伤是一种有效的治疗策略。血管内皮细胞(endothelial cell,EC)是炎症过程中各种细胞因子和生长因子作用的靶点。EC被多种因素激活后引发表型的转变有利于炎症 Inflammation is the tissue’s defensive response to injury factors, characterized by telangiectasia and inflammatory cell exudation, which play an important role in the development and progression of the disease. Inhibit the inflammatory response to improve the general condition, reduce organ damage is an effective treatment strategy. Endothelial cells (ECs) are the targets of various cytokines and growth factors in the process of inflammation. Activation of EC by a variety of factors induces phenotypic changes that favor inflammation