全世界每年有五十多万男子接受输精管结扎术做为计划生育的一种措施。虽然自1968年就有人提出该术可能对人体产生不利影响,但直到最近才引起有关人士的注意。输精管结扎的免疫应答早在1951年Voisin等人用同种的睾丸提取物加有佐剂注入雄性豚鼠下腹部皮内,引起该鼠明显的睾丸炎及间质和精曲小管内淋巴细胞,单核细胞的浸 More than half a million men worldwide undergo vasectomy as a measure of family planning every year. Although it has been suggested since 1968 that this technique may have adverse effects on the human body, it has only recently attracted the attention of those concerned. Vas deferens Ligation Immune Response As early as 1951, Voisin et al. Injected the same type of testicular extract plus adjuvant into the lower abdominal skin of male guinea pigs, causing marked orchitis and interstitial and intraperitoneal lymphocytes in the rat Immersion of nuclear cells