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成年雄性大耳白兔30只,分为5组:对照组(适宜量组)、高酪蛋白组(蛋白质占总能量25％)、高大豆蛋白组(蛋白质占总能量25％)、高脂肪组(脂肪占总能量40％)和低脂肪组(脂肪占总能量16％),饲养80天。观察不同饲料组成对家兔主功脉组织形态、血脂水平、组织中总脂含量与脂肪酸组成和体重等的影响。结果表明,主动脉粥样硬化改变,对照组少而轻,其次是高酪蛋白组和低脂肪组,高脂肪组和高大豆蛋白组病变多且重。血清TC、TG、和LDL-C高脂肪组和高酪蛋白组(除TG外)均高于对照组,高大豆蛋白组和低脂肪组(除TG外)均低于对照组,HDL-C除低脂肪组外,各组相似。主动脉中脂肪含量受饲料影响最大,实验各组均高于对照组,且P/S值也小,对心肌影响较小,且P/S值均在1.12以上。说明饲料中三大营养素组成中不但量、而且动、植比也影响主动脉粥样硬化改变的程度。
Thirty male adult male rabbits were divided into five groups: control group (suitable dose group), high casein group (protein accounted for 25% of total energy), high soybean protein group (protein accounted for 25% of total energy), high fat Group (fat 40% of total energy) and low-fat group (fat 16% of total energy), feeding 80 days. The effect of different dietary components on the morphology, blood lipid level, total lipid content, fatty acid composition and body weight of the rabbits was observed. The results showed that aortic atherosclerosis changed, the control group less and lighter, followed by high casein and low fat group, high fat group and high soybean protein group lesions more and heavier. Serum TC, TG, and LDL-C high fat group and high casein group (except TG) were higher than the control group, high soybean protein group and low fat group (except TG) were lower than the control group, HDL-C Except for the low-fat group, the groups were similar. The content of fat in the aorta was the most affected by feed, the experimental groups were higher than the control group, and the P / S value was small, the impact on the myocardial less, and the P / S values were above 1.12. This shows that not only the amount of the three major nutrients in the feed, but also the dynamic and the plantation ratio also affect the degree of aortic atherosclerosis changes.