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1 病例 例1女,6岁,因发作性睡眠3年于2001年10月20日就诊,3年来患儿白天多睡,其特点是在走路、吃饭、玩耍和听课等各种活动中突然发生,不能克制,每次持续约2~3小时,发作时不伴有肢体抽搐和肌肉纤颤,用强刺激可以唤醒,但仍呈意识模糊状态,常有尿失禁,醒后不能回忆,病初期数日或数月发生1次,近半年来,发作为数日1次或1日数次,夜间睡眠正常,无脑炎及颅脑外伤史,也无癫痫和发作性睡眠家族史。查体:神志清楚,精神好,无神经系统受损体征,心、肺、腹检查均正常,脑电图示额叶出现少量双侧同步而对称的100~200μV尖波,诊断为发作性睡眠。给予鲁米那每次20 mg,每日3次口服治疗,半月后发作停止,鲁米那减量维持,随访半年未复发,复查脑电图恢
1 Case 1 Female, 6 years old, 3 years as a result of narcolepsy Treatment on October 20, 2001, 3 years, children with more sleep during the day, which is characterized by walking, eating, playing and listening to classes and other activities suddenly occurred , Can not be restrained, each lasting about 2 to 3 hours, the onset is not associated with limb twitching and fibrillation, with strong stimulation can wake up, but still was vague state of consciousness, often urinary incontinence, wake up can not recall, early disease A few days or months occurred in the past six months, the attack for several days or 1 several times, normal night sleep, no history of encephalitis and traumatic brain injury, nor epilepsy and episodic sleep family history. Physical examination: conscious, good spirits, no signs of nervous system damage, heart, lung, abdomen were normal examination, frontal lobe EEG showed a small amount of symmetry bilateral symmetrical 100 ~ 200μV spikes, the diagnosis of narcolepsy . Given 20 mg of luminal, 3 times a day oral treatment, half a month after the onset of the disease stopped, reduction of luminal maintenance, no recurrence six months follow-up, review EEG