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我院从 1995~ 1998年 ,通过健康检查对 1551名太原地区健康人群进行腰椎骨密度( BMD)研究 ,其中男性 517人 ,女性 10 34人 ,在不同年龄段中发现骨矿峰值在 30~ 39岁 ,两性一致 ,男性保持 2 0年 ,女性 10年后骨矿含量随年龄增加而减少。女性 60岁以后 BMD降低 2 1.66% ,而男性仅3.54% ,其中 L1降低达 18.87% ,L2 与 L2 -4 降低的幅度 ,女性一致 ,男性则有显著差异。本研究认为 L2 -4男性降低的幅度不显著与腰椎退行性病变、骨质增生、骨赘形成、韧带及组织钙化有关 ,而 L1则少受此影响。同时在腰椎压缩性骨折患者中 L1最为多见均提示 L1降低的重要性 ,因而提出女性患者应用 L2 -4BMD作为骨质疏松诊断 ,是与国内外诊断的金指标一致 ,而对男性要重视 L1降低的临床意义。无论采用“局限性”骨质疏松 ,抑或作为骨质疏松诊断标准均需得到不同地区和国家进一步研究证实
In our hospital from 1995 to 1998, 1,551 healthy people in the Taiyuan region were examined for bone mineral density (BMD) by lumbar spine, including 517 males and 10 34 females. Peak bone mineralogies were observed in different age groups from 30 to 39. At the age of two, the gender is the same. Males remain for 20 years. After 10 years of female bone mineral content decreases with age. Women had a BMD reduction of 21.66% after 60 years of age compared with 3.54% for men, of which L1 decreased by 18.87%. L2 and L2 -4 decreased in women, while men had significant differences. In this study, the decrease in L2 -4 males was not significantly associated with degenerative lumbar spine disease, bone hyperplasia, osteophyte formation, ligament and tissue calcification, whereas L1 was less affected. At the same time, the most common L1 in patients with lumbar compression fractures is suggesting the importance of L1 reduction. Therefore, the use of L2 -4 BMD as a diagnosis of osteoporosis in women is consistent with the gold indicators for diagnosis at home and abroad, and L1 should be emphasized for men. Reduced clinical significance. Whether the use of “localized” osteoporosis, or as a diagnostic criteria for osteoporosis, needs to be further confirmed by different regions and countries.