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视网膜脱离的类型很多,最常见的是孔源性视网膜脱离,对它的发病机理,长期以来在临床上进行了许多研究,有些研究者从遗传倾向和遗传形式上来探讨,但大多数研究者一直在探索视网膜下积液(SRF)的来源。多年来一些研究者从解剖学特征、临床观察或动物实验,认为SRF有三种来源: (1)视网膜变性:早期Magitot在光学显微镜下证实SRF中有脱落的视网膜神经细胞和原生质碎片,故确认来自视网膜。随后Lam等发现SRF有视网膜色素上皮细胞(RPE)和许多未知类型的细胞,他们在电镜下发现SRF中有巨噬细胞。近期Toris等诱发猴视网膜脱离的SRF,在电镜下也观察到巨噬细胞。有人根据临床所见和SRF中脂蛋白成分分析,确认视网膜变性致使视网膜物质到达SRF中。
Many types of retinal detachment, the most common is rhegmatogenous retinal detachment, its pathogenesis, a lot of clinical research, some researchers from the genetic predisposition and genetic form to explore, but most researchers have been Explore the source of subretinal fluid (SRF). Over the years, some researchers have considered three sources of SRF from anatomical features, clinical observations or animal experiments: (1) Retinal Degeneration: Early Magitot confirmed the presence of exfoliated retinal neurons and protoplasmic fragments in SRF under a light microscope, Retina. Lam then found SRF retinal pigment epithelium (RPE) and many unknown types of cells, they found in the SRF macrophages. Recently, Toris induced SRF of monkey retinal detachment and macrophages were also observed under electron microscope. According to clinical findings and analysis of lipoprotein components in SRF, it was confirmed that retinal degeneration causes retinal material to reach the SRF.