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近年来研究发现人骨髓间充质干细胞在适宜的条件下可向神经细胞分化,并对脑缺血性疾病的神经功能缺损有明显的改善作用。本文就人骨髓间充质干细胞的取材来源、分离培养、细胞表面标记、神经细胞方向分化潜能及其在脑缺血性疾病应用方面的研究进展作了综述。
In recent years, it has been found that human bone marrow mesenchymal stem cells can differentiate into nerve cells under suitable conditions and have obvious improvement on neurological deficits of cerebral ischemic diseases. This review summarizes the origins of human bone marrow mesenchymal stem cells (MSCs), their isolation and culture, cell surface markers, the potential of neuronal differentiation and their application in the treatment of ischemic brain diseases.