摘 要 目的:探討餐后高血糖与心血管疾病发病的相关性。方法:收集排除重大疾病的血糖升高者432例,分为空腹血糖受损(IFG)、糖耐量异常(IGT)及糖尿病(DM)3组。观察3组患者心血管疾病发生率,及其心血管疾病危险性指标值的变化,分析餐后高血糖与这些心血管疾病危险因素的关系。结果:IGT、DM组心血管疾病的发生率明显高于IFG组(P<0.01),DM组心血管疾病的发生率高于IGT组,但差异无统计学意义;IGT、DM组心血管危险性指标明显高于IFG组(P<0.01),DM组危险性指标较IGT组升高(P<0.05)。结论:餐后高血糖参与心血管疾病发病,以IGT患者重要,IGT是心血管疾病发病高危人群,应尽早予以干预治疗,可有效预防心血管疾病的发生与发展。
　　关键词 餐后高血糖 空腹血糖受损 糖耐量异常 糖尿病 心血管疾病 心血管疾病危险性指标
　　doi:10.3969/j.issn.1007-614x.2010.25.020
　　AbstractObjective:To investigate the relation between the postprandial hyperglycemia and cardiovascular diseases.Methods:Collect 432 cases excluding seriously elevated blood sugar suffer,divided into 3 groups:the impaired fasting glucose(IFG),impaired glucose tolerance(IGT) and diabetes mellitus(DM).Through the observation of the incidence of cardiovascular disease and the changes of cardiovascular disease risk index value among 3 groups, analyze the relation between postprandial hyperglycemia and the cardiovascular disease risk factors.Results:The incidence of cardiovascular disease among IGT,DM groups was obviously higher than that of IFG group(P<0.01);the incidence of cardiovascular disease of DM group was higher than that of IGT group.But the difference was not statistically significant.The cardiovascular risk index of IGT, DM group was significantly higher than that of IFG group(P<0.01);DM group risk index was higher than that of IGT group(P<0.05).Conclusion:The postprandial hyperglycemia influences the incidence of cardiovascular disease.It focused on patients with IGT,because IGT patients had a high risk of cardiovascular diseases.Therefore,the early intervention is an effective way to prevent the occurrencedevelopment of cardiovascular disease.
　　Keywordspostprandial hyperglycemia;impaired fasting glucose;impaired glucose tolerance;diabetes;cardiovascular disease;cardiovascular disease risk indicators